Codival ADP (Oregano Emulsion) 60Pearls 300g

Product Information

Ghosh, V.; Mukherjee, A.; Chandrasekaran, N. Ultrasonic emulsification of food-grade nanoemulsion formulation and evaluation of its bactericidal activity. Ultrason. Sonochem. 2013, 20, 338–344. [ Google Scholar] [ CrossRef]

Baranauskaite, J.; Duman, G.; Corapcioglu, G.; Baranauskas, A.; Taralp, A.; Ivanauskas, L.; Bernatoniene, J. Liposomal incorporation to improve dissolution and stability of rosmarinic acid and carvacrol extracted from Oregano (O. onites L.). BioMed Res. Intern. 2018, 2018, 6147315. [ Google Scholar] [ CrossRef][ Green Version] Hosseini, S.F.; Zandi, M.; Rezaei, M.; Farahmandghavi, F. Two-step method for encapsulation of oregano essential oil in chitosan nanoparticles: Preparation, characterization and in vitro release study. Carbohydr. Polym. 2013, 95, 50–56. [ Google Scholar] [ CrossRef]

One study found that combined treatment with thyme and oregano essential oils helped reduce the production of pro-inflammatory cytokines and thereby may help attenuate colitis (a type of inflammatory bowel disease) in mice. Other evidence shows that oregano oil’s active compounds (such as thymol and carvacrol) can help fight toothaches and earaches caused by bacterial infections. A 2005 study published in the Journal of Infectious Diseases concluded,“Essential oils or their components placed in the ear canal can provide effective treatment of acute otitis media.”

Here’s the good news regarding the use of less-than-ideal antibiotics: There’s evidence that oregano essential oil can help fight at least several strains of bacteria that cause health problems that are commonly treated with antibiotics. Another advantage that encapsulation can offer is masking the intense aroma of OEO components. Carvacrol encapsulation into nanostructures, nanoliposomes, and polymeric Eudragit ® NCs were developed by Ayres Cacciatore et al. (2020), establishing that its encapsulation could be interesting to reduce its aroma due to its controlled release ( Ayres Cacciatore et al., 2020). The effect of lecithin or Tween 20 on O/W nanoemulsions encapsulating carvacrol was studied by Nash and Erk (2017), concluding that, while lecithin nanoemulsions were highly viscoelastic and gave stability to the nanoemulsion, Tween 20 did not ( Nash and Erk, 2017). Oregano oil health benefits include fighting bacterial infections, fungal infections, digestive problems, inflammatory conditions and tumor growth. Oregano’s oil is primarily made of carvacrol, while studies show that the plant’s leaves contain a variety of antioxidant compounds, such as phenols, triterpenes, rosmarinic acid, ursolic acid and oleanolic acid. Oregano Oil Benefits Singleton, V.L.; Rossi, J.A. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am. J. Enol. Vitic. 1965, 16, 144–158. [ Google Scholar]Thymol has been entrapped in other lipid and polymeric vehicles. For instance, Omonijo et al. (2018) microencapsulated thymol along with lauric acid into starch MPs with the presence or not of alginate to deliver them to pig intestinal tracts as an antibiotic substitute ( Omonijo et al., 2018). Highly stable systems were obtained with an in vitro prolonged release of loaded compounds in the case of MPs presenting alginate, using simulated salivary, gastric, and intestinal fluids. However, the efficacy of the MPs was not demonstrated. The intestinal delivery of thymol has also been assessed when microencapsulated into commercial lipid matrices containing organic acids by Choi et al. (2020), demonstrating the stability of the systems during feed pelleting and storing processes and an in vitro and in vivo sustained release of thymol in simulated gastric and intestinal fluids and pig guts, respectively ( Choi et al., 2020). In addition, oregano essential oil is unlikely to cause many of the harmful side effects that are commonly attributed to high use of antibiotics — such as increased risk for antibiotic resistance, poor gut health due to destroying beneficial probiotic bacteria, reduced vitamin absorption and leaky gut syndrome due to damage of the gastrointestinal tract’s lining. Humphrey, S.P.; Williamson, R.T. A review of saliva: Normal composition, flow, and function. J. Prosthet. Dent. 2001, 85, 162–169. [ Google Scholar] [ CrossRef] [ PubMed] Guo, Y.Q. Relationship between the zeta potential and the chemical agglomeration efficiency of fine particles in flue gas during coal combustion. Fuel 2018, 215, 757–765. [ Google Scholar] [ CrossRef] Good oral health and hygiene are necessary for adequate total health and life quality. 1 The World Health Organization in 2012 defined oral health as the state of being free from facial and oral pain, mouth infections, lesions, and other oral illnesses that hinder the individual’s ability to bite, chew, smile, or speak. 2 Insufficient oral care can negatively affect an individual’s overall health. Several diseases have originate in the oral cavity, and some drugs can endanger the health of the oral cavity. 3

Because it helps balance bacteria and fights yeast overgrowth, oregano essential oil is also a popular natural treatment for candida and SIBO. SIBO is a common digestive problem that causes gas, bloating and intolerances to many carbohydrate-containing foods (especially FODMAPs).Liu, X.; Mäki-Arvela, P.; Aho, A.; Vajglova, Z.; Gun’ko, V.M.; Heinmaa, I.; Kumar, N.; Eränen, K.; Salmi, T.; Murzin, D.Y. Zeta potential of beta zeolites: Influence of structure, acidity, pH, temperature and concentration. Molecules 2018, 23, 946. [ Google Scholar] [ CrossRef][ Green Version] Tarko, T.; Duda-Chodak, A. Influence of food matrix on the bioaccessibility of fruit polyphenolic compound. J. Agric. Food Chem. 2020, 68, 1315–1325. [ Google Scholar] [ CrossRef] For this mini-review article, an extensive search was conducted in different web search engines using keywords such as OEO, carvacrol, thymol, microencapsulation, nanoencapsulation, microcarriers, nanocarriers, MPs, NPs, MCs, NCs, biomedical and biotechnological. The search strategy was limited to publications in English and published from 2017 to 2021. Articles were classified according to the size of the OEO delivery system and listed according to their application. OEO Microencapsulation Overuse of antibiotics, and prescribing broad-spectrum drugs when they aren’t needed, can cause a range of problems. It can make the drugs less effective against the bacteria they are intended to treat by fostering the growth of antibiotic-resistant infections, and it can wipe out the body’s good bacteria (probiotics), which help digest food, produce vitamins and protect from infections, among other functions. Németh, K.; Plumb, G.W.; Berrin, J.G.; Juge, N.; Jacob, R.; Naim, H.Y.; Williamson, G. Deglycosylation by small intestinal epitherial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans. Eur. J. Clin. Nutr. 2003, 42, 29–42. [ Google Scholar] [ CrossRef] [ PubMed]